rs10096097

A SNP in the DCTN6 gene on chromosome 8. Its most notable genotype is G;G: increased Anorexia Nervosa risk

Gene
DCTN6
Location
Chr 830,169,582 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
49%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodnormal Anorexia Nervosa riskMinor · 1.021% of people
  2. A;GNot ratedunknown Anorexia Nervosa riskMinor · 1.044% of people
  3. G;GMost notableBadincreased Anorexia Nervosa riskWorth knowing · 2.035% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 21% A;G 44% G;G 35%
  • European ancestry (Utah)A;A 50% A;G 43% G;G 8%
  • Han Chinese (Beijing)A;A 2% A;G 37% G;G 61%
  • Japanese (Tokyo)A;A 4% A;G 29% G;G 66%
  • Yoruba (Nigeria)A;A 14% A;G 48% G;G 39%
  • African ancestry (Southwest US)A;A 12% A;G 47% G;G 40%
  • Chinese (Denver)A;A 5% A;G 36% G;G 60%
  • Gujarati IndianA;A 25% A;G 53% G;G 23%
  • Luhya (Kenya)A;A 15% A;G 41% G;G 45%
  • Mexican ancestry (Los Angeles)A;A 33% A;G 55% G;G 12%
  • Maasai (Kenya)A;A 22% A;G 51% G;G 27%
  • TuscanA;A 48% A;G 49% G;G 3%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs10096097 is a SNP near the membrane bound O-acyltransferase domain containing 4 MBOAT4 gene. A study of 543 German anorexia nervosa patients observed some association between the disorder and rs10096097(G;G) (nominal two-sided p = 0.031).

Source and license

Adapted from rs10096097 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.