rs10177833

A SNP in the SLC4A5 gene on chromosome 2. Its most notable genotype is C;C: possible reduction in risk for salt-induced hypertension

Gene
SLC4A5
Location
Chr 274,230,591 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
50%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodpossible reduction in risk for salt-induced hypertensionWorth knowing · 2.025% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 25%
  • European ancestry (Utah)C;C 13%
  • Han Chinese (Beijing)C;C 40%
  • Japanese (Tokyo)C;C 18%
  • Yoruba (Nigeria)C;C 25%
  • African ancestry (Southwest US)C;C 21%
  • Chinese (Denver)C;C 44%
  • Gujarati IndianC;C 5%
  • Luhya (Kenya)C;C 30%
  • Mexican ancestry (Los Angeles)C;C 32%
  • Maasai (Kenya)C;C 37%
  • TuscanC;C 16%

Other SLC4A5 SNPs

All SLC4A5 SNPs

Notes

From SNPedia

Notes

C;C

possible reduction in risk for salt-induced hypertension

References

Source and license

Adapted from rs10177833 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.