rs10178458

A SNP in the COL4A3 gene on chromosome 2. Its most notable genotype is C;T.

Gene
COL4A3
Location
Chr 2227,246,719 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
19%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedNo summary available.Typical · 0.031% of people
  2. T;TGoodcommon in clinvarTypical · 0.07% of people

On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 31% T;T 7%
  • European ancestry (Utah)C;T 20% T;T 3%
  • Han Chinese (Beijing)C;T 17% T;T <1%
  • Japanese (Tokyo)C;T 29% T;T 4%
  • Yoruba (Nigeria)C;T 44% T;T 20%
  • African ancestry (Southwest US)C;T 42% T;T 5%
  • Chinese (Denver)C;T 14% T;T 2%
  • Gujarati IndianC;T 29% T;T 2%
  • Luhya (Kenya)C;T 56% T;T 16%
  • Mexican ancestry (Los Angeles)C;T 14% T;T 2%
  • Maasai (Kenya)C;T 46% T;T 20%
  • TuscanC;T 30% T;T 3%

Other COL4A3 SNPs

All COL4A3 SNPs

Source and license

Adapted from rs10178458 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.