rs1042523

A SNP in the PCK1 gene on chromosome 20. Its most notable genotype is A;A: common in clinvar

Gene
PCK1
Location
Chr 2057,562,751 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
32%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in clinvarTypical · 0.053% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 53%
  • European ancestry (Utah)A;A 22%
  • Han Chinese (Beijing)A;A 94%
  • Japanese (Tokyo)A;A 95%
  • Yoruba (Nigeria)A;A 48%
  • African ancestry (Southwest US)A;A 40%
  • Chinese (Denver)A;A 93%
  • Gujarati IndianA;A 42%
  • Luhya (Kenya)A;A 48%
  • Mexican ancestry (Los Angeles)A;A 46%
  • Maasai (Kenya)A;A 28%
  • TuscanA;A 22%

Other PCK1 SNPs

All PCK1 SNPs

Notes

From SNPedia

Notes

rs1042523 is in linkage disequilibrium with a polymorphism that increases susceptibility to Type II Diabetes 1.27 times for carriers of the G allele

Source and license

Adapted from rs1042523 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.