rs1044009
A SNP in the NOTCH3 gene on chromosome 19. Its most notable genotype is G;G: common in clinvar
- Gene
- NOTCH3
- Location
- Chr 1915,160,960 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1044009 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 21%
- European ancestry (Utah)G;G 4%
- Han Chinese (Beijing)G;G 26%
- Japanese (Tokyo)G;G 12%
- Yoruba (Nigeria)G;G 21%
- African ancestry (Southwest US)G;G 19%
- Chinese (Denver)G;G 19%
- Gujarati IndianG;G 11%
- Luhya (Kenya)G;G 43%
- Mexican ancestry (Los Angeles)G;G 14%
- Maasai (Kenya)G;G 53%
- TuscanG;G 5%
Related
Other NOTCH3 SNPs
- rs28933696A;GCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs28933697A;GCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs28933698A;GCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs28937321A;CCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs137852641A;GCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs267606915A;TCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs864621964C;TCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
- rs864621966A;CCerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 (CADASIL)Very important
Source and license
Adapted from rs1044009 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.