rs10462021

A SNP in the PER3 gene on chromosome 1. Its most notable genotype is G;G: Strong association with DSPS

Gene
PER3
Location
Chr 17,837,073 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon/normalTypical · 0.078% of people
  2. G;GMost notableBadStrong association with DSPSImportant · 3.02% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 78% G;G 2%
  • European ancestry (Utah)A;A 68% G;G 4%
  • Han Chinese (Beijing)A;A 99% G;G 0%
  • Japanese (Tokyo)A;A 92% G;G 0%
  • Yoruba (Nigeria)A;A 87% G;G <1%
  • African ancestry (Southwest US)A;A 72% G;G 4%
  • Gujarati IndianA;A 60% G;G 5%
  • Luhya (Kenya)A;A 81% G;G 0%
  • Mexican ancestry (Los Angeles)A;A 64% G;G 5%
  • Maasai (Kenya)A;A 93% G;G 0%
  • TuscanA;A 67% G;G 0%

Other PER3 SNPs

All PER3 SNPs

Notes

From SNPedia

Notes

A 2001 study reports that a haplotype consisting of rs10462020 & rs10462021 was significantly associated with delayed phase sleep syndrome (DSPS) in our study population (Bonferroni’s corrected P = 0.037; OR 7.79; CI: 1.59–38.3).

Source and license

Adapted from rs10462021 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.