rs10464059

A SNP on chromosome 5. Its most notable genotype is A;A: Increased risk of developing Parkinson's Disease

Gene
None listed
Location
Chr 5180,367,208 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
23%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadIncreased risk of developing Parkinson's DiseaseWorth knowing · 2.08% of people
  2. A;GBadSlightly increased risk of developing Parkinson's DiseaseMinor · 1.538% of people
  3. G;GGoodNormal risk of developing Parkinson's DiseaseMinor · 1.053% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 8% A;G 38% G;G 53%
  • European ancestry (Utah)A;A <1% A;G 27% G;G 72%
  • Han Chinese (Beijing)A;A 15% A;G 50% G;G 35%
  • Japanese (Tokyo)A;A 9% A;G 46% G;G 45%
  • Yoruba (Nigeria)A;A 11% A;G 43% G;G 46%
  • African ancestry (Southwest US)A;A 16% A;G 37% G;G 47%
  • Chinese (Denver)A;A 13% A;G 47% G;G 40%
  • Gujarati IndianA;A 8% A;G 35% G;G 57%
  • Luhya (Kenya)A;A 10% A;G 45% G;G 46%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 26% G;G 74%
  • Maasai (Kenya)A;A 8% A;G 47% G;G 45%
  • TuscanA;A 0% A;G 21% G;G 79%

Source and license

Adapted from rs10464059 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.