rs1047781
A SNP in the FUT2 gene on chromosome 19. Its most notable genotype is A;A: ABH blood group "Secretor" status if Japanese
- Gene
- FUT2
- Location
- Chr 1948,703,374 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 10%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableGoodABH blood group "Secretor" status if Japanese
- A;TNot ratedABH blood group "Secretor" status if Japanese
- T;TNot ratedABH blood group "Non-Secretor" status if Japanese
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageA;A 66% A;T 29% T;T 5%
- European ancestry (Utah)A;A 100% A;T 0% T;T 0%
- Han Chinese (Beijing)A;A 33% A;T 53% T;T 13%
- Japanese (Tokyo)A;A 30% A;T 64% T;T 7%
- Yoruba (Nigeria)A;A 100% A;T 0% T;T 0%
Related
Notes
From SNPedia
Notes
rs1047781, also known as Ile129Phe, is found on chromosome 19 in the alpha(1,2)-fucosyltransferase FUT2 gene. The wild-type rs1047781(A) encodes the 'Secretor' allele, while rs1047781(T) encodes the 'nonsecretor' (se2 or sej) allele. This basis for FUT2 nonsecretor status is found primarily in Japanese. In Caucasians, nonsecretor status is associated with the se1 allele of rs601338, and rs1047781 genotype shows almost no variation. In Japanese, the se1 allele is absent, but 15% of individuals are non-secretors based on being homozygous for rs1047781(T;T).
Source and license
Adapted from rs1047781 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.