rs10491734

A SNP on chromosome 9. Its most notable genotype is T;T: 1.4x risk of early onset OCD

Gene
None listed
Location
Chr 94,482,706 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBad1.4x risk of early onset OCDTypical · 0.07% of people
  2. C;TBad1.4x risk of early onset OCDTypical · 0.036% of people
  3. C;CGoodnormalTypical · 0.057% of people

SNPedia records rs10491734 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 7% C;T 36% C;C 57%
  • European ancestry (Utah)T;T 27% C;T 50% C;C 22%
  • Han Chinese (Beijing)T;T 4% C;T 36% C;C 60%
  • Japanese (Tokyo)T;T 5% C;T 34% C;C 61%
  • Yoruba (Nigeria)T;T <1% C;T 11% C;C 88%
  • African ancestry (Southwest US)T;T 4% C;T 32% C;C 65%
  • Chinese (Denver)T;T 2% C;T 37% C;C 62%
  • Gujarati IndianT;T 9% C;T 45% C;C 47%
  • Luhya (Kenya)T;T 0% C;T 16% C;C 84%
  • Mexican ancestry (Los Angeles)T;T 10% C;T 52% C;C 38%
  • Maasai (Kenya)T;T 5% C;T 35% C;C 60%
  • TuscanT;T 10% C;T 52% C;C 38%

Source and license

Adapted from rs10491734 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.