rs1049853

A SNP in the HLA-C gene on chromosome 6. Its most notable genotype is G;G: common in clinvar

Gene
HLA-C
Location
Chr 631,269,123 (GRCh38)
Highest magnitude
0.0Typical
Tested on
AncestryDNA
Minor allele frequency
11%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.081% of people

SNPedia records rs1049853 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 81%
  • European ancestry (Utah)G;G 77%
  • Han Chinese (Beijing)G;G 79%
  • Japanese (Tokyo)G;G 83%
  • Yoruba (Nigeria)G;G 82%
  • African ancestry (Southwest US)G;G 70%
  • Chinese (Denver)G;G 79%
  • Gujarati IndianG;G 94%
  • Luhya (Kenya)G;G 92%
  • Mexican ancestry (Los Angeles)G;G 59%
  • Maasai (Kenya)G;G 90%
  • TuscanG;G 83%

Other HLA-C SNPs

All HLA-C SNPs

Source and license

Adapted from rs1049853 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.