rs1051690

A SNP in the INSR gene on chromosome 19. Its most notable genotype is T;T: common in clinvar

Gene
INSR
Location
Chr 197,116,952 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.02% of people
  2. C;CGoodcommon in complete genomicsTypical · 0.079% of people

SNPedia records rs1051690 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 2% C;C 79%
  • European ancestry (Utah)T;T 4% C;C 54%
  • Han Chinese (Beijing)T;T 0% C;C 93%
  • Japanese (Tokyo)T;T <1% C;C 84%
  • Yoruba (Nigeria)T;T 6% C;C 64%
  • African ancestry (Southwest US)T;T 4% C;C 70%
  • Chinese (Denver)T;T 0% C;C 87%
  • Gujarati IndianT;T 0% C;C 92%
  • Luhya (Kenya)T;T 2% C;C 71%
  • Mexican ancestry (Los Angeles)T;T 0% C;C 90%
  • Maasai (Kenya)T;T 1% C;C 84%
  • TuscanT;T 4% C;C 78%

Source and license

Adapted from rs1051690 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.