rs1053004

A SNP in the STAT3 gene on chromosome 17. Its most notable genotype is G;G: common in clinvar

Gene
STAT3
Location
Chr 1742,314,074 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.034% of people

SNPedia records rs1053004 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageG;G 34%
  • European ancestry (Utah)G;G 16%
  • Han Chinese (Beijing)G;G 10%
  • Japanese (Tokyo)G;G 17%
  • African ancestry (Southwest US)G;G 61%
  • Chinese (Denver)G;G 9%
  • Gujarati IndianG;G 25%
  • Luhya (Kenya)G;G 97%
  • Mexican ancestry (Los Angeles)G;G 5%
  • Maasai (Kenya)G;G 86%
  • TuscanG;G 15%

Other STAT3 SNPs

All STAT3 SNPs

Source and license

Adapted from rs1053004 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.