rs1057035
A SNP in the DICER1 gene on chromosome 14. Its most notable genotype is T;T: common in clinvar
- Gene
- DICER1
- Location
- Chr 1495,087,805 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 22%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 76%
- European ancestry (Utah)T;T 40%
- Han Chinese (Beijing)T;T 77%
- Japanese (Tokyo)T;T 82%
- Yoruba (Nigeria)T;T 96%
- African ancestry (Southwest US)T;T 86%
- Chinese (Denver)T;T 80%
- Gujarati IndianT;T 83%
- Luhya (Kenya)T;T 87%
- Mexican ancestry (Los Angeles)T;T 66%
- Maasai (Kenya)T;T 92%
- TuscanT;T 47%
Related
Other DICER1 SNPs
- rs137852976A;CDICER1-related tumor susceptibility (predicted)Very important
- rs137852977A;CDICER1-related tumor susceptibility (predicted)Very important
- rs137852978A;GDICER1-related tumor susceptibility (predicted)Very important
- rs137852979A;GDICER1-related tumor susceptibility (predicted)Very important
- rs748087536A;CDICER1-related tumor susceptibility (predicted)Very important
- rs754081635A;GDICER1-related tumor susceptibility (predicted)Very important
- rs754818927A;GDICER1-related tumor susceptibility (predicted)Very important
- rs763801533A;GDICER1-related tumor susceptibility (predicted)Very important
Source and license
Adapted from rs1057035 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.