rs1063856
A SNP in the VWF gene on chromosome 12. Its most notable genotype is T;T: common in clinvar
- Gene
- VWF
- Location
- Chr 126,044,368 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 34%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1063856 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 49%
- European ancestry (Utah)T;T 43%
- Han Chinese (Beijing)T;T 89%
- Japanese (Tokyo)T;T 85%
- Yoruba (Nigeria)T;T 14%
- African ancestry (Southwest US)T;T 14%
- Chinese (Denver)T;T 85%
- Gujarati IndianT;T 67%
- Luhya (Kenya)T;T 15%
- Mexican ancestry (Los Angeles)T;T 60%
- Maasai (Kenya)T;T 30%
- TuscanT;T 42%
Related
Other VWF SNPs
- rs41276738T;TVon Willebrand disease, type 1Very important
- rs61748477A;AVon Willebrand disease, type 2NVery important
- rs61748478C;CVon Willebrand disease, type 2NVery important
- rs61748497G;GVon Willebrand disease, type 2NVery important
- rs61750584G;GVon Willebrand disease, type 2AVery important
- rs61750595A;Alikely miscall in Ancestry V2.0 datasets; otherwise, Von Willebrand disease, type 3Very important
- rs61750612A;AVon Willebrand disease, type 3Very important
- rs61750630A;AVon Willebrand disease, type 3Very important
Notes
From SNPedia
Notes
Development of a fingerprinting panel using medically relevant polymorphisms. Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project. Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip. von Willebrand factor plasma levels, genetic variations and coronary heart disease in an older population.
Source and license
Adapted from rs1063856 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.