rs1064039(T;T)

Higher risk for age-related macular degeneration; slightly higher Alzheimers risk in Caucasians but not Asians

Magnitude
2.0Worth knowing
Repute
Bad
On SNPedia
rs1064039(A;A)Minus strand
Gene
CST3

Other genotypes of rs1064039

  1. C;TBadslightly higher risk for Alzheimers in Caucasians but not AsiansMinor · 1.2
  2. C;CGoodcommon in clinvarTypical · 0.0

All about rs1064039

Notes

From SNPedia

Higher risk (2 or 3 fold, perhaps) for age-related macular degeneration has been reported based on a relatively small study of German patients. In Caucasians but not Asians, a meta-analysis concluded that the (A) allele was associated with about a 1.5x higher risk for Alzheimers in both dominant and recessive models.

Source and license

Adapted from rs1064039(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.