rs10911193

A SNP in the LAMC1 gene on chromosome 1. Its most notable genotype is T;T.

Gene
LAMC1
Location
Chr 1183,021,513 (GRCh38)
Highest magnitude
1.9Minor
Tested on
23andMe
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodNo summary available.Typical · 0.076% of people
  2. T;TMost notableBadNo summary available.Minor · 1.92% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 76% T;T 2%
  • European ancestry (Utah)C;C 79% T;T 0%
  • Han Chinese (Beijing)C;C 87% T;T 2%
  • Japanese (Tokyo)C;C 64% T;T 7%
  • Yoruba (Nigeria)C;C 76% T;T 0%

Notes

From SNPedia

Notes

T;T

some papers suggest an increased risk of pelvic organ prolapse, but the most recent analysis does not replicate that result.

Source and license

Adapted from rs10911193 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.