rs10958409

A SNP on chromosome 8. Its most notable genotype is A;A: 1.79x increased aneurysm risk

Gene
None listed
Location
Chr 854,414,531 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
22%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBad1.79x increased aneurysm riskTypical · 0.05% of people
  2. A;GBad1.37x increased aneurysm riskTypical · 0.034% of people
  3. G;GNot ratednormalTypical · 0.060% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 5% A;G 34% G;G 60%
  • European ancestry (Utah)A;A 2% A;G 28% G;G 70%
  • Han Chinese (Beijing)A;A 9% A;G 45% G;G 46%
  • Japanese (Tokyo)A;A 7% A;G 40% G;G 53%
  • Yoruba (Nigeria)A;A 1% A;G 25% G;G 74%
  • African ancestry (Southwest US)A;A 5% A;G 28% G;G 67%
  • Chinese (Denver)A;A 6% A;G 40% G;G 54%
  • Gujarati IndianA;A 8% A;G 49% G;G 44%
  • Luhya (Kenya)A;A <1% A;G 26% G;G 74%
  • Mexican ancestry (Los Angeles)A;A 18% A;G 49% G;G 33%
  • Maasai (Kenya)A;A 1% A;G 21% G;G 78%
  • TuscanA;A 3% A;G 27% G;G 71%

Conditions, medicines and genes

Notes

From SNPedia

Notes

23andMe blog aneurysm *rs700651 2 G 1.18x risk 1.56x risk *rs10958409 8 A 1.37x risk 1.79x risk *rs1333040 9 T 1.29x risk 1.67x risk Brain Aneurysm

Source and license

Adapted from rs10958409 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.