rs10975200

A SNP in the KANK1 gene on chromosome 9. Its most notable genotype is A;A.

Gene
KANK1
Location
Chr 9571,085 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
32%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.049% of people
  2. C;CNot rated>1.14x riskTypical · 0.00% of people
  3. C;TNot rated1.14x riskTypical · 0.00% of people

On SNPedia: (A;A), (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 49% C;C 0% C;T 0%
  • European ancestry (Utah)A;A 69% C;C 0% C;T 0%
  • Han Chinese (Beijing)A;A 18% C;C 0% C;T 0%
  • Japanese (Tokyo)A;A 37% C;C 0% C;T 0%
  • Yoruba (Nigeria)A;A 48% C;C 0% C;T 0%
  • African ancestry (Southwest US)A;A 51% C;C 0% C;T 0%
  • Chinese (Denver)A;A 13% C;C 0% C;T 0%
  • Gujarati IndianA;A 77% C;C 0% C;T 0%
  • Luhya (Kenya)A;A 51% C;C 0% C;T 0%
  • Mexican ancestry (Los Angeles)A;A 53% C;C 0% C;T 0%
  • Maasai (Kenya)A;A 52% C;C 0% C;T 0%
  • TuscanA;A 70% C;C 0% C;T 0%

Conditions, medicines and genes

Notes

From SNPedia

Notes

This SNP is located in the gene KANK1. This variant has been associated with risk of Multiple Sclerosis . The study analyzed 931 family trios and several different control sets. The p-value for the association was 9.945e-06 http://www.gwascentral.org/marker/HGVM3682090/results.

Source and license

Adapted from rs10975200 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.