rs10982256

A SNP in the WHRN gene on chromosome 9. Its most notable genotype is C;C: 1.5x risk

Gene
WHRN
Location
Chr 9114,498,554 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
40%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot rated1.5x riskTypical · 0.046% of people
  2. C;TNot rated1.3x riskTypical · 0.037% of people
  3. G;GNot ratedNo summary available.Typical · 0.00% of people
  4. T;TNot ratednormalTypical · 0.018% of people

On SNPedia: (C;C), (C;T), (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 46% C;T 37% G;G 0% T;T 18%
  • European ancestry (Utah)C;C 25% C;T 46% G;G 0% T;T 29%
  • Han Chinese (Beijing)C;C 20% C;T 50% G;G 0% T;T 31%
  • Japanese (Tokyo)C;C 16% C;T 57% G;G 0% T;T 27%
  • Yoruba (Nigeria)C;C 97% C;T 3% G;G 0% T;T 0%
  • African ancestry (Southwest US)C;C 65% C;T 33% G;G 0% T;T 2%
  • Chinese (Denver)C;C 18% C;T 49% G;G 0% T;T 33%
  • Gujarati IndianC;C 21% C;T 55% G;G 0% T;T 25%
  • Luhya (Kenya)C;C 98% C;T 2% G;G 0% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 48% C;T 41% G;G 0% T;T 10%
  • Maasai (Kenya)C;C 76% C;T 23% G;G 0% T;T 1%
  • TuscanC;C 20% C;T 46% G;G 0% T;T 34%

Conditions, medicines and genes

Other WHRN SNPs

All WHRN SNPs

Notes

From SNPedia

Notes

rs10982256 has been reported in a large study to be associated with bipolar disorder. The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.26 (CI 1.08-1.47), and for homozygotes, 1.47 (CI 1.24-1.74).

Source and license

Adapted from rs10982256 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.