rs10988802
A SNP on chromosome 9. Its most notable genotype is G;G: common in complete genomics
- Gene
- None listed
- Location
- Chr 995,614,417 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 17%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 7 HapMap populations.
- AverageG;G 63%
- European ancestry (Utah)G;G 74%
- Han Chinese (Beijing)G;G 71%
- Japanese (Tokyo)G;G 74%
- Yoruba (Nigeria)G;G 52%
- African ancestry (Southwest US)G;G 53%
- Gujarati IndianG;G 61%
- Maasai (Kenya)G;G 58%
Notes
From SNPedia
Notes
rs10988802 is a SNP located in the PTCH1 gene. This gene is a member of the patched gene family and a receptor for sonic hedgehog. This gene functions as a tumor suppressor and has a role during embryonic development. Other SNPs in this gene have been associated with various cancers. rs10988802 was strongly associated with plasma chemerin levels in a genome-wide association study involving 525 patients from the San Antonio Family Heart Study Cohort, originally described here . Chemerin, also known as retinoic acid receptor responder protein 2 is thought to promote angiogenesis within expanding adipose tissue.
Source and license
Adapted from rs10988802 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.