rs10995356

A SNP in the LOC107984012 gene on chromosome 10. Its most notable genotype is A;A: Likely more reward dependent

Gene
LOC107984012
Location
Chr 1062,896,153 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
33%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedLikely more reward dependentMinor · 1.512% of people
  2. A;GNot ratedNo tendency in either directionMinor · 1.034% of people
  3. G;GNot ratedLikely less reward dependentMinor · 1.554% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 12% A;G 34% G;G 54%
  • European ancestry (Utah)A;A 26% A;G 42% G;G 33%
  • Han Chinese (Beijing)A;A 12% A;G 40% G;G 48%
  • Japanese (Tokyo)A;A 10% A;G 41% G;G 50%
  • Yoruba (Nigeria)A;A <1% A;G 10% G;G 90%
  • African ancestry (Southwest US)A;A 0% A;G 26% G;G 74%
  • Chinese (Denver)A;A 8% A;G 51% G;G 40%
  • Gujarati IndianA;A 27% A;G 51% G;G 23%
  • Luhya (Kenya)A;A 0% A;G 5% G;G 96%
  • Mexican ancestry (Los Angeles)A;A 28% A;G 48% G;G 24%
  • Maasai (Kenya)A;A 2% A;G 16% G;G 82%
  • TuscanA;A 19% A;G 47% G;G 34%

Source and license

Adapted from rs10995356 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.