rs11073328

A SNP in the FAM98B gene on chromosome 15. Its most notable genotype is T;T: increased longevity?

Gene
FAM98B
Location
Chr 1538,472,642 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
9%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodnormalTypical · 0.082% of people
  2. T;TMost notableNot ratedincreased longevity?Worth knowing · 2.02% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageC;C 82% T;T 2%
  • European ancestry (Utah)C;C 82% T;T 2%
  • Han Chinese (Beijing)C;C 81% T;T 2%
  • Japanese (Tokyo)C;C 77% T;T 2%
  • Yoruba (Nigeria)C;C 99% T;T 0%
  • African ancestry (Southwest US)C;C 95% T;T 0%
  • Gujarati IndianC;C 70% T;T 9%
  • Luhya (Kenya)C;C 90% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 56% T;T 5%
  • Maasai (Kenya)C;C 86% T;T 0%

Notes

From SNPedia

Notes

This snp is in a gene which shows protein-protein interaction only with a mitochondrial protein. Mentioned in retracted

T;T

very limited evidence, but this appears to be the rare genotype across many populations. May interact with mitochondria?

Source and license

Adapted from rs11073328 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.