rs11132186

A SNP on chromosome 4. Its most notable genotype is T;T: 0.5x decreased risk for bladder cancer

Gene
None listed
Location
Chr 4183,517,570 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
AncestryDNA
Minor allele frequency
29%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GNot ratedNo summary available.Typical · 0.054% of people
  2. G;TNot ratedNo summary available.Typical · 0.040% of people
  3. T;TMost notableGood0.5x decreased risk for bladder cancerWorth knowing · 2.06% of people

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 2 HapMap populations.

  • AverageG;G 54% G;T 40% T;T 6%
  • European ancestry (Utah)G;G 46% G;T 48% T;T 6%
  • Yoruba (Nigeria)G;G 62% G;T 32% T;T 6%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs11132186 is a SNP on ch 4 near the inhibitor of growth family, member 2 ING2 gene. A pathway-based case-control approach assessing the association of 207 SNPs in 26 DNA repair genes in 800 patients with bladder cancer concluded that the odds ratio of the homozygous variant rs11132186(T;T) genotype was 0.52 (CI: 0.32-0.83, p = .005).

Source and license

Adapted from rs11132186 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.