rs11190870

A SNP on chromosome 10. Its most notable genotype is T;T: Possibly even more increased risk of scoliosis

Gene
None listed
Location
Chr 10101,219,450 (GRCh38)
Highest magnitude
2.5Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
42%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TBadPossibly increased risk of scoliosisWorth knowing · 2.046% of people
  2. T;TMost notableBadPossibly even more increased risk of scoliosisWorth knowing · 2.538% of people

On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 46% T;T 38%
  • European ancestry (Utah)C;T 43% T;T 42%
  • Han Chinese (Beijing)C;T 49% T;T 26%
  • Japanese (Tokyo)C;T 57% T;T 26%
  • Yoruba (Nigeria)C;T 44% T;T 44%
  • African ancestry (Southwest US)C;T 40% T;T 44%
  • Chinese (Denver)C;T 50% T;T 28%
  • Gujarati IndianC;T 43% T;T 55%
  • Luhya (Kenya)C;T 48% T;T 32%
  • Mexican ancestry (Los Angeles)C;T 36% T;T 50%
  • Maasai (Kenya)C;T 48% T;T 33%
  • TuscanC;T 49% T;T 37%

Conditions, medicines and genes

Notes

From SNPedia

Notes

The T allele of this SNP is associated with an increased risk of scoliosis in adolescent Japanese girls. nature.com

Source and license

Adapted from rs11190870 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.