rs11391

A SNP in the HDAC2 gene on chromosome 6. Its most notable genotype is A;A.

Gene
HDAC2
Location
Chr 6113,940,851 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
8%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.086% of people

SNPedia records rs11391 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 86%
  • European ancestry (Utah)A;A 73%
  • Han Chinese (Beijing)A;A 83%
  • Japanese (Tokyo)A;A 80%
  • Yoruba (Nigeria)A;A 99%
  • African ancestry (Southwest US)A;A 95%
  • Chinese (Denver)A;A 85%
  • Gujarati IndianA;A 70%
  • Luhya (Kenya)A;A 98%
  • Mexican ancestry (Los Angeles)A;A 83%
  • Maasai (Kenya)A;A 99%
  • TuscanA;A 78%

Other HDAC2 SNPs

All HDAC2 SNPs

Notes

From SNPedia

Notes

Polymorphism within HDAC2 (Histone Deacetylase 2). Has been examined as a predictor of tumour recurrence in carcinoma patients, but unlike other SNPs analysed ( Rs1741981 or Rs2547547 ), did not correlate with recurrence-free survival. ==References==

Source and license

Adapted from rs11391 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.