rs1143646

A SNP in the HTT gene on chromosome 4. Its most notable genotype is T;T: common in complete genomics

Gene
HTT
Location
Chr 43,146,926 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
2%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.096% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 7 HapMap populations.

  • AverageT;T 96%
  • European ancestry (Utah)T;T 91%
  • Han Chinese (Beijing)T;T 100%
  • Japanese (Tokyo)T;T 100%
  • Yoruba (Nigeria)T;T 100%
  • Gujarati IndianT;T 93%
  • Mexican ancestry (Los Angeles)T;T 97%
  • TuscanT;T 92%

Source and license

Adapted from rs1143646 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.