rs11541790

A SNP in the TTR gene on chromosome 18. Its most notable genotype is C;T: TTR-related amyloidosis

Gene
TTR
Location
Chr 1831,592,956 (GRCh38)
Highest magnitude
5.5Very important
Tested on
23andMe, AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableBadTTR-related amyloidosisVery important · 5.50% of people
  2. C;CGoodcommon in clinvarTypical · 0.0100% of people

SNPedia records rs11541790 on the minus strand: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;T 0% C;C 100%
  • European ancestry (Utah)C;T 0% C;C 100%
  • Han Chinese (Beijing)C;T 0% C;C 100%
  • Japanese (Tokyo)C;T 0% C;C 100%
  • Yoruba (Nigeria)C;T 0% C;C 100%

Other TTR SNPs

All TTR SNPs

Source and license

Adapted from rs11541790 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.