rs11556045

A SNP in the HEXB gene on chromosome 5. Its most notable genotype is A;A: common in clinvar

Gene
HEXB
Location
Chr 574,689,390 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
21%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in clinvarTypical · 0.060% of people
  2. A;GGoodbenign polymorphismTypical · 0.035% of people
  3. G;GGoodbenign polymorphismTypical · 0.05% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 60% A;G 35% G;G 5%
  • European ancestry (Utah)A;A 55% A;G 41% G;G 4%
  • Han Chinese (Beijing)A;A 63% A;G 35% G;G 3%
  • Japanese (Tokyo)A;A 66% A;G 32% G;G 3%
  • Yoruba (Nigeria)A;A 59% A;G 34% G;G 8%
  • African ancestry (Southwest US)A;A 47% A;G 47% G;G 5%
  • Chinese (Denver)A;A 77% A;G 21% G;G 2%
  • Gujarati IndianA;A 57% A;G 35% G;G 8%
  • Luhya (Kenya)A;A 44% A;G 46% G;G 10%
  • Mexican ancestry (Los Angeles)A;A 61% A;G 35% G;G 4%
  • Maasai (Kenya)A;A 60% A;G 31% G;G 9%
  • TuscanA;A 74% A;G 24% G;G 3%

Other HEXB SNPs

All HEXB SNPs

Source and license

Adapted from rs11556045 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.