rs11662595

A SNP in the HRH4 gene on chromosome 18. Its most notable genotype is G;G.

Gene
HRH4
Location
Chr 1824,477,006 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
7%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon on affy axiom dataTypical · 0.086% of people
  2. G;GMost notableNot ratedNo summary available.Worth knowing · 2.0<1% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 86% G;G <1%
  • European ancestry (Utah)A;A 85% G;G 0%
  • Han Chinese (Beijing)A;A 92% G;G 0%
  • Japanese (Tokyo)A;A 81% G;G <1%
  • Yoruba (Nigeria)A;A 97% G;G 0%
  • Chinese (Denver)A;A 93% G;G 0%
  • Gujarati IndianA;A 93% G;G 0%
  • Luhya (Kenya)A;A 94% G;G 0%
  • Mexican ancestry (Los Angeles)A;A 70% G;G 2%
  • Maasai (Kenya)A;A 80% G;G <1%
  • TuscanA;A 78% G;G 0%

Other HRH4 SNPs

All HRH4 SNPs

Notes

From SNPedia

Notes

Histamine pharmacogenomics

Source and license

Adapted from rs11662595 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.