rs11669576
A SNP in the LDLR gene on chromosome 19. Its most notable genotype is G;G: common in clinvar
- Gene
- LDLR
- Location
- Chr 1911,111,624 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 8%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 83%
- European ancestry (Utah)G;G 87%
- Han Chinese (Beijing)G;G 99%
- Japanese (Tokyo)G;G 98%
- Yoruba (Nigeria)G;G 57%
- African ancestry (Southwest US)G;G 58%
- Chinese (Denver)G;G 99%
- Gujarati IndianG;G 98%
- Luhya (Kenya)G;G 57%
- Mexican ancestry (Los Angeles)G;G 96%
- Maasai (Kenya)G;G 76%
- TuscanG;G 91%
Related
Other LDLR SNPs
- rs121908027-;-familial hypercholesterolemiaVery important
- rs5933C;GFamilial HypercholesterolemiaVery important
- rs2228671A;CFamilial HypercholesterolemiaVery important
- rs2569548C;TFamilial HypercholesterolemiaVery important
- rs11547917A;CFamilial HypercholesterolemiaVery important
- rs13306512A;CFamilial HypercholesterolemiaVery important
- rs13306515A;CFamilial HypercholesterolemiaVery important
- rs28941776A;GFamilial HypercholesterolemiaVery important
Notes
From SNPedia
Notes
Genetic study evaluating LDLR polymorphisms and Alzheimer's disease.
Source and license
Adapted from rs11669576 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.