rs11701
A SNP in the ANG gene on chromosome 14. Its most notable genotype is T;T: common in clinvar
- Gene
- ANG
- Location
- Chr 1420,693,894 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 12%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageT;T 75%
- European ancestry (Utah)T;T 74%
- Han Chinese (Beijing)T;T 96%
- Japanese (Tokyo)T;T 95%
- Yoruba (Nigeria)T;T 78%
- African ancestry (Southwest US)T;T 74%
- Gujarati IndianT;T 74%
- Luhya (Kenya)T;T 63%
- Mexican ancestry (Los Angeles)T;T 66%
- Maasai (Kenya)T;T 56%
- TuscanT;T 73%
Notes
From SNPedia
Notes
The common form at this site in most populations is rs11701(T), and the variant form is rs11701(G). Having at least one copy of this variant form, rs11701(G), has been associated with an increased incidence of ALS in Scottish and Irish populations studied, but not in populations from the U.S., Sweden, or England. *rs11701 In Irish amyotrophic lateral sclerosis patients, there was a significant allelic association with the rs11701 SNP & a new mutation (K40I) that potentially inhibits angiogenin function.
Source and license
Adapted from rs11701 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.