rs12194974

A SNP in the LIN28B gene on chromosome 6. Its most notable genotype is G;G: common in complete genomics

Gene
LIN28B
Location
Chr 6104,956,323 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
6%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.090% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageG;G 90%
  • European ancestry (Utah)G;G 75%
  • Han Chinese (Beijing)G;G 100%
  • Japanese (Tokyo)G;G 100%
  • Yoruba (Nigeria)G;G 92%
  • African ancestry (Southwest US)G;G 90%
  • Gujarati IndianG;G 89%
  • Luhya (Kenya)G;G 96%
  • Mexican ancestry (Los Angeles)G;G 91%
  • Maasai (Kenya)G;G 90%
  • TuscanG;G 75%

Source and license

Adapted from rs12194974 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.