rs12251307

A SNP on chromosome 10. Its most notable genotype is C;C: common in complete genomics

Gene
None listed
Location
Chr 106,081,532 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
19%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.062% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 62%
  • European ancestry (Utah)C;C 81%
  • Han Chinese (Beijing)C;C 66%
  • Japanese (Tokyo)C;C 66%
  • Yoruba (Nigeria)C;C 38%
  • African ancestry (Southwest US)C;C 46%
  • Chinese (Denver)C;C 67%
  • Gujarati IndianC;C 65%
  • Luhya (Kenya)C;C 45%
  • Mexican ancestry (Los Angeles)C;C 70%
  • Maasai (Kenya)C;C 53%
  • TuscanC;C 85%

Notes

From SNPedia

Notes

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis. Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions. Overview of the Rapid Response data. Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.

Source and license

Adapted from rs12251307 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.