rs1230345

A SNP in the WISP3 gene on chromosome 6. Its most notable genotype is G;G: common in clinvar

Gene
WISP3
Location
Chr 6112,061,110 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
30%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.046% of people
  2. A;CNot ratedNo summary available.Typical · 0.00% of people

SNPedia records rs1230345 on the minus strand: (C;C), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 46% A;C 0%
  • European ancestry (Utah)G;G 58% A;C 0%
  • Han Chinese (Beijing)G;G 45% A;C 0%
  • Japanese (Tokyo)G;G 57% A;C 0%
  • Yoruba (Nigeria)G;G 29% A;C 0%
  • African ancestry (Southwest US)G;G 21% A;C 0%
  • Chinese (Denver)G;G 48% A;C 0%
  • Gujarati IndianG;G 72% A;C 0%
  • Luhya (Kenya)G;G 36% A;C 0%
  • Mexican ancestry (Los Angeles)G;G 53% A;C 0%
  • Maasai (Kenya)G;G 36% A;C 0%
  • TuscanG;G 51% A;C 0%

Other WISP3 SNPs

All WISP3 SNPs

Notes

From SNPedia

Notes

rs1230345 was associated with schizophrenia in a Illuminia HumanExome chip comparison of n=977 patients and controls. http://www.ncbi.nlm.nih.gov/pubmed/27028512

Source and license

Adapted from rs1230345 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.