rs12366144
A SNP in the TRPC6 gene on chromosome 11. Its most notable genotype is A;A: common in clinvar
- Gene
- TRPC6
- Location
- Chr 11101,476,362 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- Not on consumer chips
- Minor allele frequency
- 27%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 52%
- European ancestry (Utah)A;A 52%
- Han Chinese (Beijing)A;A 93%
- Japanese (Tokyo)A;A 69%
- Yoruba (Nigeria)A;A 14%
- African ancestry (Southwest US)A;A 25%
- Chinese (Denver)A;A 91%
- Gujarati IndianA;A 60%
- Luhya (Kenya)A;A 19%
- Mexican ancestry (Los Angeles)A;A 74%
- Maasai (Kenya)A;A 18%
- TuscanA;A 61%
Related
Other TRPC6 SNPs
- i5005218C;TFocal segmental glomerulosclerosis 2Important
- i5005219A;TFocal segmental glomerulosclerosis 2Important
- i5005220A;TFocal segmental glomerulosclerosis 2Important
- i5005221A;GFocal segmental glomerulosclerosis 2Important
- i5005222A;GFocal segmental glomerulosclerosis 2Important
- rs121434390G;TFocal segmental glomerulosclerosis 2Important
- rs121434391C;TFocal segmental glomerulosclerosis 2Important
- rs121434392A;TFocal segmental glomerulosclerosis 2Important
Source and license
Adapted from rs12366144 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.