rs12413409

A SNP in the CNNM2 gene on chromosome 10. Its most notable genotype is G;G.

Gene
CNNM2
Location
Chr 10102,959,339 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
14%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedNo summary available.Typical · 0.074% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 74%
  • European ancestry (Utah)G;G 86%
  • Han Chinese (Beijing)G;G 50%
  • Japanese (Tokyo)G;G 53%
  • Yoruba (Nigeria)G;G 95%
  • African ancestry (Southwest US)G;G 91%
  • Chinese (Denver)G;G 50%
  • Gujarati IndianG;G 55%
  • Luhya (Kenya)G;G 94%
  • Mexican ancestry (Los Angeles)G;G 66%
  • Maasai (Kenya)G;G 92%
  • TuscanG;G 78%

Conditions, medicines and genes

Other CNNM2 SNPs

All CNNM2 SNPs

Notes

From SNPedia

Notes

Based on a large study (~6,000 cases and 14,000 controls) of both European and Japanese populations, the rs12413409(G) allele has been associated with higher risk of aneurysm, with an odds ratio per allele of 1.29 (CI:1.19-1.40, p=1.2e-09). Also: 23andMe blog blood pressure Coronary Heart Disease High Blood Pressure (Hypertension)

Source and license

Adapted from rs12413409 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.