rs12416000

A SNP on chromosome 10. Its most notable genotype is A;A: Neanderthal gene

Gene
None listed
Location
Chr 104,797,975 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
11%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNeanderthal geneWorth knowing · 2.02% of people
  2. A;GNot ratedmixed homo-sapiens (human) and NeanderthalMinor · 1.019% of people
  3. G;GNot ratedhomo sapiens gene (not Neanderthal)Typical · 0.179% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 2% A;G 19% G;G 79%
  • European ancestry (Utah)A;A 2% A;G 20% G;G 79%
  • Han Chinese (Beijing)A;A 3% A;G 26% G;G 72%
  • Japanese (Tokyo)A;A 4% A;G 24% G;G 72%
  • Yoruba (Nigeria)A;A 0% A;G 0% G;G 100%
  • African ancestry (Southwest US)A;A 0% A;G 7% G;G 93%
  • Chinese (Denver)A;A 3% A;G 30% G;G 67%
  • Gujarati IndianA;A 2% A;G 36% G;G 62%
  • Luhya (Kenya)A;A 0% A;G 7% G;G 93%
  • Mexican ancestry (Los Angeles)A;A 2% A;G 33% G;G 66%
  • Maasai (Kenya)A;A 1% A;G 15% G;G 84%
  • TuscanA;A 2% A;G 14% G;G 84%

Notes

From SNPedia

Notes

G;G

This is the human, homo sapiens version of the gene, not the neanderthal version.

Source and license

Adapted from rs12416000 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.