rs12567209
A SNP on chromosome 1. Its most notable genotype is G;G: common in complete genomics
- Gene
- None listed
- Location
- Chr 1162,066,689 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 11%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 76%
- European ancestry (Utah)G;G 86%
- Han Chinese (Beijing)G;G 68%
- Japanese (Tokyo)G;G 71%
- Yoruba (Nigeria)G;G 84%
- African ancestry (Southwest US)G;G 86%
- Chinese (Denver)G;G 67%
- Gujarati IndianG;G 46%
- Luhya (Kenya)G;G 84%
- Mexican ancestry (Los Angeles)G;G 81%
- Maasai (Kenya)G;G 74%
- TuscanG;G 91%
Notes
From SNPedia
Notes
rs10494366, rs4657139 and rs16847548 were significantly associated with adjusted QT interval in whites. relative hazard of SCD associated with each C allele at rs16847548 was 1.31. rs12567209 was also independently associated with SCD in whites (relative hazard 0.57, 95% confidence interval 0.39 to 0.83, P=0.003). No significant associations observed in blacks. Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population. Genetic variation in NOS1AP is associated with sudden cardiac death: evidence from the Rotterdam Study.
Source and license
Adapted from rs12567209 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.