rs12608932(C;C)

Small increase in ALS risk; better lithium response in ALS patients

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
24%Average of 11 populations
On SNPedia
rs12608932(C;C)
Gene
UNC13A

Frequency

Share of people with C;C in each HapMap population.

  • Japanese (Tokyo)60%
  • Han Chinese (Beijing)54%
  • Chinese (Denver)50%
  • Gujarati Indian25%
  • Yoruba (Nigeria)16%
  • European ancestry (Utah)12%
  • African ancestry (Southwest US)12%
  • Mexican ancestry (Los Angeles)12%
  • Tuscan10%
  • Maasai (Kenya)7%
  • Luhya (Kenya)6%

Other genotypes of rs12608932

  1. A;AGoodlowest ALS risk among rs12608932 genotypesTypical · 0.035% of people
  2. A;CBadSlight (1.5x) increase in ALS riskMinor · 1.541% of people

All about rs12608932

Notes

From SNPedia

see discussion at rs12608932

Source and license

Adapted from rs12608932(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.