rs12621278
A SNP in the ITGA6 gene on chromosome 2. Its most notable genotype is A;A: common in complete genomics
- Gene
- ITGA6
- Location
- Chr 2172,446,825 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 9%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageA;A 81%
- European ancestry (Utah)A;A 92%
- Han Chinese (Beijing)A;A 50%
- Japanese (Tokyo)A;A 64%
- Yoruba (Nigeria)A;A 100%
- African ancestry (Southwest US)A;A 98%
- Chinese (Denver)A;A 57%
- Gujarati IndianA;A 78%
- Mexican ancestry (Los Angeles)A;A 95%
- TuscanA;A 96%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
According to a 23andMe report, the rs12621278(A;A) genotype is associated with 2.4 times higher risk of progression of prostate cancer.
Source and license
Adapted from rs12621278 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.