rs12734338

A SNP in the PPP1R12B gene on chromosome 1. Its most notable genotype is C;T: Gender=Male (if data is from a DNA chip)

Gene
PPP1R12B
Location
Chr 1202,500,595 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableGoodGender=Male (if data is from a DNA chip)Minor · 1.049% of people
  2. T;TGoodGender=Female (if data is from a DNA chip)Minor · 1.050% of people

On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 49% T;T 50%
  • European ancestry (Utah)C;T 52% T;T 48%
  • Han Chinese (Beijing)C;T 48% T;T 52%
  • Japanese (Tokyo)C;T 53% T;T 47%
  • Yoruba (Nigeria)C;T 48% T;T 50%
  • African ancestry (Southwest US)C;T 41% T;T 59%
  • Chinese (Denver)C;T 47% T;T 51%
  • Gujarati IndianC;T 57% T;T 43%
  • Luhya (Kenya)C;T 47% T;T 52%
  • Mexican ancestry (Los Angeles)C;T 46% T;T 54%
  • Maasai (Kenya)C;T 50% T;T 50%
  • TuscanC;T 52% T;T 49%

Notes

From SNPedia

Notes

Due to homology between a region on the Y chromosome and chromosome 1, a genotyping test for rs12734338 will return a result of (C;T) when males are tested and a result of (T;T) when females are tested.,

Source and license

Adapted from rs12734338 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.