rs12926089

A SNP in the CLCN7 gene on chromosome 16. Its most notable genotype is C;C: common in complete genomics

Gene
CLCN7
Location
Chr 161,452,856 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
9%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.084% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 84%
  • European ancestry (Utah)C;C 80%
  • Han Chinese (Beijing)C;C 100%
  • Japanese (Tokyo)C;C 100%
  • Yoruba (Nigeria)C;C 66%
  • African ancestry (Southwest US)C;C 75%
  • Chinese (Denver)C;C 99%
  • Gujarati IndianC;C 92%
  • Luhya (Kenya)C;C 68%
  • Mexican ancestry (Los Angeles)C;C 88%
  • Maasai (Kenya)C;C 75%
  • TuscanC;C 78%

Notes

From SNPedia

Notes

Analysis of variation in expression of autosomal dominant osteopetrosis type 2: searching for modifier genes. Polymorphisms of the CLCN7 gene are associated with BMD in women. CLCN7 polymorphisms and bone mineral density in healthy premenopausal white women and in white men.

Source and license

Adapted from rs12926089 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.