rs13010627
A SNP in the CASP10 gene on chromosome 2. Its most notable genotype is G;G: common in clinvar
- Gene
- CASP10
- Location
- Chr 2201,209,375 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 3%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 6 HapMap populations.
- AverageG;G 95%
- European ancestry (Utah)G;G 92%
- Han Chinese (Beijing)G;G 100%
- Japanese (Tokyo)G;G 100%
- Yoruba (Nigeria)G;G 100%
- Mexican ancestry (Los Angeles)G;G 90%
- TuscanG;G 88%
Related
Notes
From SNPedia
Notes
Previous studies had suggested that the minor allele of this SNP might influence breast cancer. However, a 2009 European study of 30,000 breast cancer cases, compared to 30,000 controls, found no association, or as they put it, "persuasive evidence against an overall association between invasive breast cancer risk and (this SNP)".
Source and license
Adapted from rs13010627 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.