rs13202464

A SNP in the FGFR3P1 gene on chromosome 6. Its most notable genotype is A;G: likely to be a carrier of one HLA-B27 allele, possible risk for B27 Syndromes.

Gene
FGFR3P1
Location
Chr 631,376,806 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
6%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon/normalTypical · 0.088% of people
  2. A;GMost notableBadlikely to be a carrier of one HLA-B27 allele, possible risk for B27 Syndromes.Important · 3.012% of people
  3. G;GBadlikely to carry two HLA-B27 alleles, possible risk for B27 Syndromes.Important · 3.0<1% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 88% A;G 12% G;G <1%
  • European ancestry (Utah)A;A 89% A;G 11% G;G <1%
  • Han Chinese (Beijing)A;A 82% A;G 18% G;G 0%
  • Japanese (Tokyo)A;A 68% A;G 29% G;G 3%
  • Yoruba (Nigeria)A;A 100% A;G 0% G;G 0%
  • African ancestry (Southwest US)A;A 93% A;G 7% G;G 0%
  • Chinese (Denver)A;A 87% A;G 13% G;G 0%
  • Gujarati IndianA;A 72% A;G 27% G;G 1%
  • Luhya (Kenya)A;A 99% A;G <1% G;G 0%
  • Mexican ancestry (Los Angeles)A;A 86% A;G 14% G;G 0%
  • Maasai (Kenya)A;A 94% A;G 6% G;G 0%
  • TuscanA;A 95% A;G 5% G;G 0%

Notes

From SNPedia

Notes

See: HLA-B27 Syndromes. Not all alleles of HLA-B27 are at risk for B27 Syndromes, please check the HLA-B27 page for details.

A;G

See details at: HLA-B27 Syndromes. Not all alleles of HLA-B27 are at risk for B27 Syndromes, please check the HLA-B27 page for details.

G;G

See details at: HLA-B27 Syndromes. Not all allelles of HLA-B27 are at risk for B27 Syndromes, please check the HLA-B27 page for details.

Source and license

Adapted from rs13202464 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.