rs13254738

A SNP in the PRNCR1 gene on chromosome 8. Its most notable genotype is A;C: 1.18x prostate cancer risk

Gene
PRNCR1
Location
Chr 8127,092,098 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
48%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;CMost notableBad1.18x prostate cancer riskWorth knowing · 2.043% of people
  2. C;CBad1.18x prostate cancer riskWorth knowing · 2.039% of people

On SNPedia: (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;C 43% C;C 39%
  • European ancestry (Utah)A;C 39% C;C 15%
  • Han Chinese (Beijing)A;C 51% C;C 44%
  • Japanese (Tokyo)A;C 53% C;C 38%
  • Yoruba (Nigeria)A;C 29% C;C 60%

Notes

From SNPedia

Notes

rs13254738 increases susceptibility to Prostate cancer 1.18 times for carriers of the C allele

Source and license

Adapted from rs13254738 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.