rs13317

A SNP in the FGFR1 gene on chromosome 8. Its most notable genotype is T;T: common in clinvar

Gene
FGFR1
Location
Chr 838,411,996 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
28%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.053% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 53%
  • European ancestry (Utah)T;T 51%
  • Han Chinese (Beijing)T;T 39%
  • Japanese (Tokyo)T;T 38%
  • Yoruba (Nigeria)T;T 68%
  • African ancestry (Southwest US)T;T 61%
  • Chinese (Denver)T;T 42%
  • Gujarati IndianT;T 82%
  • Luhya (Kenya)T;T 59%
  • Mexican ancestry (Los Angeles)T;T 47%
  • Maasai (Kenya)T;T 44%
  • TuscanT;T 56%

Notes

From SNPedia

Notes

Interferon regulatory factor 6 (IRF6) and fibroblast growth factor receptor 1 (FGFR1) contribute to human tooth agenesis. Impaired FGF signaling contributes to cleft lip and palate. A genome-wide linkage scan for cleft lip and cleft palate identifies a novel locus on 8p11-23. Studies of genes in the FGF signaling pathway and oral clefts with or without dental anomalies.

Source and license

Adapted from rs13317 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.