rs13429458

A SNP in the THADA gene on chromosome 2. Its most notable genotype is A;A: common in complete genomics

Gene
THADA
Location
Chr 243,411,699 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
17%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedcommon in complete genomicsTypical · 0.067% of people
  2. A;CGood0.67x Lower risk of PCOS for Han ChineseTypical · 0.030% of people
  3. C;CGood0.67x Lower risk of PCOS for Han ChineseTypical · 0.03% of people

On SNPedia: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 67% A;C 30% C;C 3%
  • European ancestry (Utah)A;A 83% A;C 15% C;C 2%
  • Han Chinese (Beijing)A;A 60% A;C 35% C;C 5%
  • Japanese (Tokyo)A;A 51% A;C 37% C;C 13%
  • Yoruba (Nigeria)A;A 65% A;C 33% C;C 2%
  • African ancestry (Southwest US)A;A 74% A;C 26% C;C 0%
  • Chinese (Denver)A;A 65% A;C 34% C;C <1%
  • Gujarati IndianA;A 74% A;C 24% C;C 2%
  • Luhya (Kenya)A;A 55% A;C 44% C;C 2%
  • Mexican ancestry (Los Angeles)A;A 78% A;C 22% C;C 0%
  • Maasai (Kenya)A;A 60% A;C 35% C;C 5%
  • TuscanA;A 71% A;C 28% C;C 1%

Source and license

Adapted from rs13429458 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.