rs13431828

A SNP in the IL1RL1 gene on chromosome 2. Its most notable genotype is C;C: common in complete genomics

Gene
IL1RL1
Location
Chr 2102,338,193 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
16%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.069% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 69%
  • European ancestry (Utah)C;C 77%
  • Han Chinese (Beijing)C;C 83%
  • Japanese (Tokyo)C;C 74%
  • Yoruba (Nigeria)C;C 48%
  • African ancestry (Southwest US)C;C 51%
  • Chinese (Denver)C;C 87%
  • Gujarati IndianC;C 84%
  • Luhya (Kenya)C;C 56%
  • Mexican ancestry (Los Angeles)C;C 74%
  • Maasai (Kenya)C;C 51%
  • TuscanC;C 69%

Conditions, medicines and genes

Other IL1RL1 SNPs

All IL1RL1 SNPs

Notes

From SNPedia

Notes

rs13431828 is a SNP in the Interleukin-1 receptor-like 1 IL1RL1 gene. 206 adult patients with surgery-unresponsive chronic rhinosinusitis and 196 matched controls were used to conclude that several SNPs in the IL1RL1 gene appeared to be protective against this condition. rs13431828 showed the highest association with CRS (p = 0.008; odds ratio 0.56; CI: 0.36-0.86).

Source and license

Adapted from rs13431828 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.