rs1385699

A SNP in the EDA2R gene on chromosome X. Its most notable genotype is T;T: increased risk of baldness

Gene
EDA2R
Location
Chr X66,605,144 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
31%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodslightly less likely to go baldMinor · 1.542% of people
  2. C;TNot rated?Typical · 0.06% of people
  3. T;TMost notableBadincreased risk of baldnessWorth knowing · 2.053% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 7 HapMap populations.

  • AverageC;C 42% C;T 6% T;T 53%
  • European ancestry (Utah)C;C 15% C;T 14% T;T 71%
  • Han Chinese (Beijing)C;C 0% C;T 0% T;T 100%
  • Japanese (Tokyo)C;C 0% C;T 0% T;T 100%
  • Yoruba (Nigeria)C;C 100% C;T 0% T;T 0%
  • African ancestry (Southwest US)C;C 73% C;T 20% T;T 7%
  • Gujarati IndianC;C 8% C;T 3% T;T 89%
  • Luhya (Kenya)C;C 95% C;T 3% T;T 2%

Conditions, medicines and genes

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

rs1385699, also known as Arg57Lys, is a SNP in the ectodysplasin A2 receptor EDAR2 gene. This gene is located on the X chromosome. The rs1385699(T) allele, which is the most common in European populations, was found to be associated with androgenetic alopecia in a case-control study of 400 males.

C;C

decreased risk of baldness

T;T

slightly higher risk of baldness

Source and license

Adapted from rs1385699 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.