rs1406844918

A SNP. Its most notable genotype is C;T: Short sleeper; rare mutation reported to reduce sleep time needed

Gene
None listed
Highest magnitude
4.9Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedShort sleeper; rare mutation reported to reduce sleep time neededVery important · 4.9
  2. T;TGoodcommon/normal; 8+ hours of sleep typically neededTypical · 0.0

On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

rs1406844918 represents a rare mutation known as the Y206H (p.Tyr206His) mutation in the neuropeptide S receptor 1 NPSR1 gene, located on chromosome 7. In 2019, a report was published indicating this mutation was responsible for the short sleep phenotype observed in a (single) Chinese family. It is apparently a gain-of-function mutation and thus able to be inherited in a dominant manner. People with this trait [familial natural short sleep (FNSS)] have a lifelong tendency to sleep only 4 to 6 hours per night while still feeling sufficiently rested.

C;T

see text and links via main rs-page

Source and license

Adapted from rs1406844918 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.